Risk of bias 1 article

Risk of bias is the possibility that systematic features of a study cause its results to deviate from the truth in a predictable direction. Appraisal considers domains such as participant selection, allocation, blinding, outcome measurement, missing data and selective reporting, with the relevant domains depending on study design. In dental evidence reviews, these judgements affect how confidently results can be interpreted or combined. Risk of bias concerns internal validity and is different from random imprecision or simple reporting quality.